Home | About Us | Editorial Board | Current Issue | Archives | Search | Instructions | Subscription | Feedback | e-Alerts | Login 
Journal of Indian Society of Pedodontics and Preventive Dentistry Official publication of Indian Society of Pedodontics and Preventive Dentistry
 Users Online: 1982  
 
  Print this page Email this page   Small font sizeDefault font sizeIncrease font size


 
EDITORIAL
Year : 2007  |  Volume : 25  |  Issue : 2  |  Page : 64
 

HIV - Interpreted, intervened, interrupted . . .?


Editor-in-Chief, JISPPD, Nair Hospital Dental College, Dr. A. L. Nair Road, Mumbai Central, Mumbai - 400 008, India

Correspondence Address:
S G Damle
Editor-in-Chief, JISPPD, Nair Hospital Dental College, Dr. A. L. Nair Road, Mumbai Central, Mumbai - 400 008
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0970-4388.33449

Rights and Permissions

 



How to cite this article:
Damle S G. HIV - Interpreted, intervened, interrupted . . .?. J Indian Soc Pedod Prev Dent 2007;25:64

How to cite this URL:
Damle S G. HIV - Interpreted, intervened, interrupted . . .?. J Indian Soc Pedod Prev Dent [serial online] 2007 [cited 2019 Dec 9];25:64. Available from: http://www.jisppd.com/text.asp?2007/25/2/64/33449


The spread of human immunodeficiency virus (HIV) across the world has taken all of us by surprise. HIV infection in humans has now gained pandemic proportions. More than 25 million people have died due to this unsparing disease since it was first recognized in 1981, making it the most destructive pandemic recorded in history. The Indian scenario of HIV/acquired immunodeficiency syndrome (AIDS) is very grim. According to the HIV Sentinel Surveillance Survey report (2006), India has an estimated 5.1 million individuals living with HIV/AIDS and a prevalence of 0.91%.

HIV is a retrovirus that causes AIDS, in which the host immune system begins to fail leading to development of life-threatening opportunistic infections. The discovery of anti-­retroviral drugs and development of the highly active anti-retroviral therapy has given hope to millions of people across the globe. The current treatment modality focuses on suppressing HIV in order to delay the onset of AIDS and prolonging the life of the infected patients. This treatment method cannot remove the virus from the body.

As a major breakthrough in our battle against HIV/AIDS, a team of scientists has found an enzyme 'Tre Recombinase' that can remove the viral DNA from the infected host cell in infected tissue cultures. Research on this novel approach against the menace of HIV is underway at the Max Planck Institute, University of Hamburg. Although the enzyme is still far from use as a treatment option, it offers a ray of hope to the HIV-infected individuals worldwide. Hurdles that the enzyme will have to face before it can be used in humans include the establishment of safety, efficacy and methods to efficiently deliver the enzyme for its optimal function. Nevertheless, the enzymatic approach might form a useful basis for the development of future anti-HIV therapies.

The ultimate aim in the management of HIV/AIDS is the development of an effective anti-HIV vaccine as it would be an affordable option, independent of patient compliance, and serve as a means of primary prevention of HIV. However, the development of an effective anti-HIV vaccine has eluded researchers due to the highly mutagenic nature of HIV. Hence, although we have partly interpreted this disease and showed promises in intervening its progress, we are still far from its successful interruption.


    Figures

  [Figure - 1]



 

Top
Print this article  Email this article
Previous article Next article

    

 
  Search
 
   Next article
   Previous article 
   Table of Contents
  
 
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Article in PDF (72 KB)
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
* Registration required (free)  


    Article Figures

 Article Access Statistics
    Viewed3331    
    Printed133    
    Emailed2    
    PDF Downloaded303    
    Comments [Add]    

Recommend this journal


Contact us | Sitemap | Advertise | What's New | Copyright and Disclaimer 
 © 2005 - Journal of Indian Society of Pedodontics and Preventive Dentistry | Published by Wolters Kluwer - Medknow 
Online since 1st May '05