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Journal of Indian Society of Pedodontics and Preventive Dentistry Official publication of Indian Society of Pedodontics and Preventive Dentistry
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 ORIGINAL ARTICLE
Year : 2016  |  Volume : 34  |  Issue : 3  |  Page : 210-216

Evaluation of antimicrobial effect of azadirachtin plant extract (Soluneem ) on commonly found root canal pathogenic microorganisms (viz. Enterococcus faecalis) in primary teeth: A microbiological study


1 Department of Pedodontics and Preventive Dentistry, College of Dental Sciences and Research Centre, Ahmedabad, Gujarat, India
2 Department of Dentistry, Faculty of Dentistry, SEGi University, Kota Damansara PJU 5, 47810 Petaling Jaya, Selangor, Malaysia

Correspondence Address:
Karthik Venkataraghavan
Department of Pedodontics and Preventive Dentistry, College of Dental Sciences and Research Centre, Ahmedabad, Gujarat
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0970-4388.186741

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Aim: The aim of this study is to evaluate the antimicrobial activity of Soluneem when used as an irrigating solution along with other commonly used irrigating solution sodium hypochlorite (NaOCl) against Enterococcus faecalis. Materials and Methods: Microorganism used in this study was E. faecalis (Microbial Type Culture Collection 439). Test substance used was Soluneem , which was obtained from Vittal Mallya Scientific Research Foundation (VMSRF), Bengaluru. This study was conducted in a microbiology laboratory (Biocare Research India Pvt., Ltd. Laboratory, Ahmedabad, Gujarat) to evaluate the antimicrobial effect of Soluneem (Azadirachtin) on E. faecalis. Antimicrobial activity testing was performed using the macrobroth dilution method according to the Clinical Laboratory Standards Institute guidelines. All determinations were performed thrice. Results: Minimum bactericidal concentration (MBC) was seen as 2.6% for Soluneem while the same was seen at 0.1% for NaOCl. Independent sample t-test was carried out to compare the MBC of Soluneem and NaOCl, which showed that there was no statistically significant difference between them, i.e., 2.6% Soluneem was as effective as 0.1% NaOCl. Conclusion: Soluneem showed antimicrobial activity against E. faecalis at various concentrations. It was also found that the efficacy of Soluneem at 2.6% concentration and above was relatively similar to that of gold standard irrigating solution (NaOCl) on inhibition of E. faecalis.






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  2005 - Journal of Indian Society of Pedodontics and Preventive Dentistry | Published by Wolters Kluwer - Medknow 
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