Journal of Indian Society of Pedodontics and Preventive Dentistry
Journal of Indian Society of Pedodontics and Preventive Dentistry
                                                   Official journal of the Indian Society of Pedodontics and Preventive Dentistry                           
Year : 2006  |  Volume : 24  |  Issue : 2  |  Page : 63--68

Genetic sensitivity to the bitter taste of 6-n propylthiouracil: A new risk determinant for dental caries in children


S Rupesh, Ullal Anand Nayak 
 Department of Pedodontics and Preventive Dentistry, Rajah Muthiah Dental College and Hospital, Annamalai University, Tamil Nadu, India

Correspondence Address:
Ullal Anand Nayak
18, Faculty Quarters, Annamalai Nagar - 608002, Tamil Nadu
India

The aims of the present study were to contrast the prevalence of dental caries in children with different genetic sensitivity levels to the bitter taste of 6-n-propylthiouracil (PROP) and to determine the taste quality and taste intensity preferences of food products among the taster and nontaster groups. Overall caries experience (dmfs/DMFS) was significantly higher for nontasters than tasters. Caries experience on the available surfaces (dfs/DFS) was found to be significantly higher in nontasters than in medium tasters and in medium tasters than in supertasters (r=-0.41, P <0.001). Majority of the nontasters were sweet likers and preferred strong tasting food products, while majority of the supertasters were sweet dislikers and preferred weak tastes. There was a significant increase in the overall caries experience in the population, as the genetic ability to detect PROP taste decreased ( P <0.001). After all associated factors (age, gender, race, number of teeth and OHI-S) were controlled; multiple linear regression analyses revealed that taste was the only variable significantly related to overall caries experience.


How to cite this article:
Rupesh S, Nayak UA. Genetic sensitivity to the bitter taste of 6-n propylthiouracil: A new risk determinant for dental caries in children.J Indian Soc Pedod Prev Dent 2006;24:63-68


How to cite this URL:
Rupesh S, Nayak UA. Genetic sensitivity to the bitter taste of 6-n propylthiouracil: A new risk determinant for dental caries in children. J Indian Soc Pedod Prev Dent [serial online] 2006 [cited 2022 Jan 16 ];24:63-68
Available from: https://www.jisppd.com/article.asp?issn=0970-4388;year=2006;volume=24;issue=2;spage=63;epage=68;aulast=Rupesh;type=0