Journal of Indian Society of Pedodontics and Preventive Dentistry
Journal of Indian Society of Pedodontics and Preventive Dentistry
                                                   Official journal of the Indian Society of Pedodontics and Preventive Dentistry                           
Year : 2011  |  Volume : 29  |  Issue : 2  |  Page : 84--89

The genetic basis of tooth agenesis: Basic concepts and genes involved


Sharat Chandra Pani 
 Department of Pediatric Dentistry, Riyadh Colleges of Dentistry and Pharmacy, Riyadh, Saudi Arabia

Correspondence Address:
Sharat Chandra Pani
Department of Pediatric Dentistry, Riyadh Colleges of Dentistry and Pharmacy, PO Box 84891 Riyadh
Saudi Arabia

Tooth agenesis is the most prevalent craniofacial congenital malformation in humans. While tooth agenesis may be associated with several syndromes, non-syndromic hypodontia refers to the congenital absence of a few teeth in the absence of any other deformity. Recent advances in molecular genetics have made it possible to identify the exact genes responsible for the development of teeth and trace the mutations that cause hypodontia. This paper reviews the literature regarding the genetic basis of non-syndromic tooth agenesis, methods used to study it, and the genes that have been definitively implicated in the agenesis of human dentition.


How to cite this article:
Pani SC. The genetic basis of tooth agenesis: Basic concepts and genes involved.J Indian Soc Pedod Prev Dent 2011;29:84-89


How to cite this URL:
Pani SC. The genetic basis of tooth agenesis: Basic concepts and genes involved. J Indian Soc Pedod Prev Dent [serial online] 2011 [cited 2021 Oct 28 ];29:84-89
Available from: https://www.jisppd.com/article.asp?issn=0970-4388;year=2011;volume=29;issue=2;spage=84;epage=89;aulast=Pani;type=0