Journal of Indian Society of Pedodontics and Preventive Dentistry
Journal of Indian Society of Pedodontics and Preventive Dentistry
                                                   Official journal of the Indian Society of Pedodontics and Preventive Dentistry                           
Year : 2021  |  Volume : 39  |  Issue : 2  |  Page : 113--119

Effectiveness of the use of xylitol chewing gum in prevention of dental caries: A systematic review


Kelly Rodrigues Mota1, João Vitor Farias da Silva2, Cristine D’Almeida Borges3, Priscylla Gonçalves Correia Leite de Marcelos1, Pamella Recco Alvares4, Valdeci Elias dos Santos Júnior1 
1 Department of Paediatric Dentistry, Federal University of Alagoas, Maceió, Brazil
2 Department of Medicine, Federal University of Sergipe, São Cristóvão, Brazil
3 Department of Periodontics, Federal University of Alagoas, Maceió, Brazil
4 Department of Pathology, University of Pernambuco, Recife, Brazil

Correspondence Address:

This systematic review of the literature assessed the effectiveness of using chewing gum containing only xylitol compared to prevention strategies or placebo in reducing the incidence of carious lesions in children using data obtained from randomized controlled trials. Electronic search was carried out in PubMed MEDLINE, Latin American and Caribbean Literature on the Health Science, Web of Science, Scopus, Science Direct, and Scientific Electronic Library Online through the period between 2000 and 2020. Included clinical studies were done in children when the xylitol was dispensed in gum and the preventive effect of xylitol on tooth decay was compared to other preventive strategies or control groups. The studies were evaluated for their quality to obtain the level of evidence. The preventive fraction of each study was extracted. Two hundred studies were found. After analyzing the inclusion and removal of duplicates, only five studies were analyzed for the quality of evidence. With the analysis through the Grading of Recommendations Assessment, Development, and Evaluation system, it was possible to verify the very low level of scientific evidence on the effectiveness of gums containing only xylitol for the prevention of caries in children. The preventive fraction obtained varied between − 0.31 and 0.57 depending on the compared prevention strategy. The conflicting results, limitations, and inconsistencies of the studies allow us to establish that there is insufficient evidence to support the use of gums containing only xylitol for the prevention of caries in children. Other properly designed clinical trials need to be carried out.


How to cite this article:
Mota KR, da Silva JV, Borges CD, Leite de Marcelos PG, Alvares PR, Santos Júnior VE. Effectiveness of the use of xylitol chewing gum in prevention of dental caries: A systematic review.J Indian Soc Pedod Prev Dent 2021;39:113-119


How to cite this URL:
Mota KR, da Silva JV, Borges CD, Leite de Marcelos PG, Alvares PR, Santos Júnior VE. Effectiveness of the use of xylitol chewing gum in prevention of dental caries: A systematic review. J Indian Soc Pedod Prev Dent [serial online] 2021 [cited 2021 Nov 29 ];39:113-119
Available from: https://www.jisppd.com/article.asp?issn=0970-4388;year=2021;volume=39;issue=2;spage=113;epage=119;aulast=Mota;type=0